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Research Article | Volume: 2, Issue: 1 Published Date: April 27, 2026 Demographic and Regional Disparities due to Peritonitis-Related Mortality in the US: A 21-Year Retrospective Analysis of the CDC WONDER DatabaseAuthor(s): Abeera Nauman, Muhammad Ahmed, Shree Rath, Nahal Qureshi, Muhammad Faisal Iqbal and Abdul Rahim Soroush* Abstract: Background: Peritonitis is a critical surgical emergency with high mortality. Despite medical advances, disparities persist in outcomes across demographic and regional groups in the United States. Methods: We conducted a retrospective analysis of the CDC WONDER Multiple Cause of Death database (1999 ? 2020), identifying adults aged ≥ 25 years with peritonitis-related mortality using ICD-10 codes K65.0, K65.8, and K65.9. Crude mortality rates (CMRs) and age-adjusted mortality rates (AAMRs) per 100,000 population were calculated. Temporal trends were evaluated using Join point regression. |
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Case Report | Volume: 1, Issue: 1 Published Date: July 26, 2025 A Rare Case of Primary Sclerosing Cholangitis in a 20-Year-Old ManAuthor(s): Dr. Guru Yogendra M* and Dr. Anil Kumar Sakalecha Abstract: Primary Sclerosing Cholangitis is a rare, long-lasting cholestatic liver disease characterised by advanced inflammation and fibrosis of the intrahepatic and extrahepatic bile ducts. It is infrequent in young adults, making the primary diagnosis and management serious to prevent difficulties. A 20-year-old male presented with icterus, pruritus, fever, and yellowish discoloration of urine. Laboratory investigations exposed deranged liver function tests, including elevated bilirubin and cholestatic enzymes. The patient underwent Magnetic Resonance Cholangiopancreatography, which established characteristic features of PSC such as intrahepatic bile duct beading, multifocal strictures, periductal fibrosis, caudate lobe hypertrophy, and bile duct wall thickening. |
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