KOS Journal of Biotechnology and Pharmaceutical Sciences

About Journal

Biotechnology Journal is a peer-reviewed publication dedicated to the latest research and developments in the field of biotechnology. The journal covers a wide range of topics, including genetic engineering, molecular biology, bioinformatics, bioprocessing, and the application of biotechnological innovations in medicine, agriculture, and environmental sustainability. It aims to highlight groundbreaking research that drives advancements in both basic and applied biotechnological sciences. By publishing original studies, reviews, and technical articles, the journal provides a platform for researchers, industry professionals, and policymakers to share knowledge and collaborate on the development of novel biotechnological solutions.

Research Topics

Biotechnology; Pharmaceutical Sciences; Biopharmaceuticals; Drug Discovery; Drug Development; Biomedical Research; Pharmacology; Bioprocessing; Clinical Trials; Regulatory Affairs; Molecular Biology; Genetic Engineering; Recombinant DNA Technology; Genomics; Proteomics; Transcriptomics; Cell Culture; Stem Cell Research; CRISPR Technology; Synthetic Biology; Drug Formulation; Controlled Release Systems; Nanomedicine; Liposomal Drug Delivery; Transdermal Patches; Injectable Drug Delivery; Oral Drug Formulations; Biodegradable Polymers; Targeted Drug Delivery; Vaccine Development; Drug Absorption; Drug Metabolism; Bioavailability; Half-Life; Drug Distribution; Drug Excretion; Therapeutic Index; Dose-Response Relationship; Enzyme Inhibition; Pharmacogenomics; Bioprocess Engineering; Fermentation Technology; Downstream Processing; Bioreactors; Monoclonal Antibodies; Protein Purification; Cell Line Development; Quality Control in Biopharma; Good Manufacturing Practices (GMP); Biologics Manufacturing


Latest Articles

Research Article | Volume: 1, Issue: 1 Published Date: May 28, 2025

Nanomedicine and Al: The Future of Targeted Drug Delivery and Diagnostics

Authors: Soren Falkner

Abstract: Nanomedicine, an interdisciplinary field leveraging nanotechnology, is poised to revolutionize healthcare through the development of highly specific drug delivery systems and ultra-sensitive diagnostic tools. By manipulating materials at the nanoscale. (1-100 nanometers), researchers are engineering novel approaches to overcome limitations in conventional medicine. Targeted drug delivery via nanoparticles offers the potential to enhance therapeutic efficacy by precisely delivering payloads to diseased cells or tissues, minimizing off-target effects and improving patient outcomes.


Research Article | Volume: 1, Issue: 1 Published Date: April 16, 2025

Bioanalytical Method Development and Validation for the Estimation of Ripretinib and its Pharmacokinetic Study in Rat Plasma by LC-MS

Authors: Shyamala M*, Vishal P and Lalini V

Abstract: In this study, sensitive liquid chromatography coupled with the tandem mass spectrometry (LC-MS/ MS) method was developed and validated for the determination of Ripretinib in rat plasma. Liquid-liquid extraction using dichloromethane allowed successful separation of the analyte and internal standard (IS) Sorafenib on an Agilent Zorbax SB C18column with a mobile phase consisted of a mixture of Tetrahydrofuran: 0.2% formic acid solution (80:20, % v/v) delivered at a flow rate of 0.9 mL/min. Mass spectrometric detection was operated in positive multiple reaction monitoring (MRM) mode. The ion transitions monitored were 510.09 → 94.06 for Ripretinib, m/z 465.09 → 185.07 for the IS.